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- Arthur Pavot, Jihad Mallat, Nicolas Vangrunderbeeck, Didier Thevenin, and Malcolm Lemyze.
- Department of Respiratory and Critical Care Medicine, Schaffner Hospital, Lens Intensive Care Unit, Arras Hospital, Arras, France.
- Medicine (Baltimore). 2017 Oct 1; 96 (41): e8248.
RationaleMechanical ventilation of severe acute asthma is still considered a challenging issue, mainly because of the gas trapping phenomenon with the potential for life-threatening barotraumatic pulmonary complications.Patient ConcernsHerein, we describe 2 consecutive cases of near-fatal asthma for whom the recommended protective mechanical ventilation approach using low tidal volume of 6 mL/kg and small levels of PEEP was rapidly compromised by giant pneumomediastinum with extensive subcutaneousemphysema.DiagnosesNear fatal asthma.InterventionA rescue therapeutic strategy combining extracorporeal CO2 removal membrane with ultra-protective extremely low tidal volume (3 mL/kg) ventilation was applied.OutcomesBoth patients survived hospital discharge.LessonsThese 2 cases indicate that ECCO2R associated with ultra-protective ventilation could be an alternative to surgery in case of life-threatening barotrauma occurring under mechanical ventilation.
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