• The Laryngoscope · Dec 2010

    Comparative Study

    Intralesional corticosteroid injection and dilatation provides effective management of subglottic stenosis in Wegener's granulomatosis.

    • Nikolaus E Wolter, Eng Hooi Ooi, and Ian J Witterick.
    • Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.
    • Laryngoscope. 2010 Dec 1; 120 (12): 2452-5.

    Objectives/HypothesisTo describe our experience with the use of intralesional corticosteroid injection and dilatation (ILCD) in the management of subglottic stenosis (SGS).Study DesignRetrospective chart review.MethodsA retrospective chart review was performed of all patients with SGS requiring ILCD, from 2003 to 2008, at the Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Hospital, Toronto, Canada.ResultsTwelve patients with SGS underwent 36 ILCD operations with a mean of three procedures per patient. We identified eight patients with Wegener's granulomatosis (WG) and four patients without WG. The eight WG patients received an average of 3.37 procedures, whereas non-WG patients required an average of 2.25 procedures. This maintained airway patency and symptom control for an average of 11.9 and 8.1 months, respectively. Only one complication was identified, and no long-term sequelae were found. No patients required new tracheotomies and one patient with a previous tracheotomy was successfully decannulated.ConclusionsOur data supports the use of ILCD as a safe and effective treatment of SGS in both WG and non-WG patients.

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