• Respiration · Jan 2008

    Review

    Pathophysiology of the pleura.

    • Michael A Jantz and Veena B Antony.
    • Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, Gainesville, Fla, USA.
    • Respiration. 2008 Jan 1; 75 (2): 121-33.

    AbstractThe pleural mesothelial cell is an essential cell in maintaining the normal homeostasis of the pleural space and it is also a central component of the pathophysiologic processes affecting the pleural space. In this review, we will review the defense mechanisms of the pleural mesothelium and changes in pleural physiology as a result of inflammatory, infectious, and malignant conditions with a focus on cytokine and chemokine networks. We will also review the processes involved in the pathogenesis of pleural fibrosis.Copyright (c) 2008 S. Karger AG, Basel

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