• Patompong Ungprasert, Anawin Sanguankeo, Sikarin Upala, and Promporn Suksaranjit.
• From the Department of Medicine, Faculty of Medicine Siriraj Hospital, Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang road, Bangkok, 10700, Thailand and Department of Cardiology, University of Utah, School of Medicine, 30 N 1900 E, Salt Lake City, Utah, 84132, USA patompong.ungprasert@bassett.org.
• QJM. 2014 Oct 1; 107 (10): 793-7.

BackgroundSeveral chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, have been shown to increase venous thromboembolism (VTE) risk but the data on psoriasis is unclear.MethodsWe conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio or standardized incidence ratio comparing VTE risk in patients with psoriasis vs. non-psoriasis participants. Pooled risk ratio and 95% confidence intervals were calculated using a random effect, generic inverse variance method.ResultFour studies were identified and included in our data analysis. The pooled risk ratio of VTE in patients with psoriasis was 1.46 (95% CI, 1.29-1.66). The statistical heterogeneity of this meta-analysis was high with an I(2) of 86%.ConclusionOur study demonstrated a statistically significant increased VTE risk among patients with psoriasis.© The Author 2014. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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