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Int. J. Infect. Dis. · Aug 2020
Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19: Insights from simultaneous familial Kawasaki Disease cases.
- R Ebina-Shibuya, H Namkoong, Y Shibuya, and N Horita.
- Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: risa.ebina-shibuya@nih.gov.
- Int. J. Infect. Dis. 2020 Aug 1; 97: 371-373.
AbstractRecently, an increasing number of SARS-CoV-2 patients with COVID-19 syndrome, which overlaps with Kawasaki Disease (KD), have been reported, supporting the suggestion that infection is one of the triggers of KD. We summarized the reports of simultaneous familial KD cases to better understand the etiopathogenesis of both KD and Multisystem Inflammatory Syndrome in Children (MIS-C) related to COVID-19. Here we discuss the etiology of these syndromes from the point of view of infection and genetic susceptibility.Published by Elsevier Ltd.
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