• Revue médicale de Liège · Jul 2018

    Case Reports

    [Primary malignant melanoma of vagina].

    • M Daix, P Dillies, A Gueuning, L Watkins-Masters, and F Gielen.
    • Service de Gynécologie-Obstétrique, CHC Saint-Vincent, Rocourt (Liège), Belgique.
    • Rev Med Liege. 2018 Jul 1; 73 (7-8): 413-418.

    AbstractThe primary vaginal melanoma is a rare aggressive tumour with a poor prognosis. The average age at diagnosis is 60, and there are no known risk factors. The establishment of a classification system and treatment protocols are made difficult because there are so few cases. The 5-year survival rate is estimated at no more than ten per cent. We report a case of an inoperable primary vaginal melanoma in a 58-year old woman. There were metastatic lymph nodes in the lumbo-aortic region, but no extension to bone or viscera. She was treated with nivolumab as monotherapy. Clinical and radiological evolution were both favourable, and the treatment was well tolerated.

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