• Nutr Metab Cardiovasc Dis · Apr 2021

    Evacuation after the Great East Japan Earthquake is an independent factor associated with hyperuricemia: The Fukushima Health Management Survey.

    • Kazuya Honda, Kanako Okazaki, Kenichi Tanaka, Junichiro J Kazama, Shigeatsu Hashimoto, Tetsuya Ohira, Akira Sakai, Seiji Yasumura, Masaharu Maeda, Hirooki Yabe, Yuriko Suzuki, Mitsuaki Hosoya, Atsushi Takahashi, Hironori Nakano, Fumikazu Hayashi, Masanori Nagao, Hiromasa Ohira, Michio Shimabukuro, Hitoshi Ohto, and Kenji Kamiya.
    • Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan; Department of Endocrinology, Metabolism, Diabetology, and Nephrology, Fukushima Medical University Aizu Medical Center, Aizuwakamatsu, Japan.
    • Nutr Metab Cardiovasc Dis. 2021 Apr 9; 31 (4): 1177-1188.

    Background And AimsOn March 11, 2011, the Great East Japan Earthquake occurred in Japan, with a nuclear accident subsequently occurring at the Fukushima Daiichi Nuclear Power Plant. The disaster forced many evacuees to change particular aspects of their lifestyles. This study assessed the association between evacuation and hyperuricemia based on the Fukushima Health Management Survey from a lifestyle and socio-psychological perspective.Methods And ResultsThis cross-sectional study included 22,812 residents (9391 men and 13,297 women) who underwent both the Comprehensive Health Check and the Mental Health and Lifestyle Survey in fiscal year 2011. Associations between hyperuricemia and lifestyle- and disaster-related factors including evacuation were estimated using a logistic and liner regression analysis. With hyperuricemia defined as uric acid levels >7.0 mg/dL for men and >6.0 mg/dL for women, significant associations were observed between evacuation and hyperuricemia in men (the multivariate-adjusted odds ratio 1.20, 95% confidence interval, 1.05-1.36, p = 0.005), but not in women. In the multivariate-adjusted multiple liner regression analysis, evacuation had significant and positive associations with uric acid levels both in men (β = 0.084, p = 0.002) and women (β = 0.060, p < 0.001).ConclusionEvacuation after a natural disaster is an independent factor associated with hyperuricemia.Copyright © 2021 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

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