• N Unal, J C Pompe, W P Holland, I Gültuna, P E Huygen, K Jabaaij, C Ince, B Saygin, and H A Bruining.
• Department of Surgery, University Hospital Rotterdam, The Netherlands.
• Intensive Care Med. 1995 Feb 1; 21 (2): 142-8.

ObjectivesThe purpose of this study was to build an experimental set-up to assess continuously the humidification, heating and resistance properties of heat-moisture exchangers (HMEs) under clinical conditions.DesignThe experimental set-up consists of a patient model, measurement systems and a ventilator.SettingSurgical ICU, University Hospital of Rotterdam.MaterialsA clinically used HME.Measurements And ResultsThe air flow, pressure in the ventilation circuit, pressure difference over the HME, and partial water vapour pressure and temperature at each side of the HME were measured. The resistance, absolute humidity, humidification efficiency and temperature difference at the patient side of the HME were calculated. Measurements were performed during 24 h. The temperature output, humidity output and lung mechanics of the patient model were similar to values found in mechanically ventilated patients. The measurement system was in agreement with the ISO draft standard and was capable of measuring dynamic variation of water and heat exchange over the range of a clinically used ventilator setting.ConclusionThe experimental set-up described is reliable for evaluating HMEs and can also be used for future clinical evaluation of HMEs. The main advantages of this set-up over those described previously are: (i) measurements of dynamic variations of water and heat exchange; (ii) on-line measurements of expiratory, as well as inspiratory resistance.

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