• R Hanafi, P-A Roger, B Perin, G Kuchcinski, N Deleval, F Dallery, D Michel, L Hacein-Bey, J-P Pruvo, O Outteryck, and J-M Constans.
• From the Department of Neuroradiology (R.H., G.K., J.-P.P., O.O.), University Hospital of Lille, Hôpital Roger Salengro, Lille, France riyad.hanafi@chru-lille.fr.
• AJNR Am J Neuroradiol. 2020 Aug 1; 41 (8): 1384-1387.

AbstractCoronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of "endotheliitis" associated with this novel coronavirus.© 2020 by American Journal of Neuroradiology.

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