• Neurosurgery · Jan 2022

    Review

    Neuropathology of Pediatric Brain Tumors: A Concise Review.

    • Bonnie L Cole.
    • Department of Laboratories, Seattle Children's Hospital , Seattle , Washington , USA.
    • Neurosurgery. 2022 Jan 1; 90 (1): 7157-15.

    AbstractPediatric brain tumors are an incredibly diverse group of neoplasms and neuropathological tumor classification is an essential part of patient care. Classification of pediatric brain tumors has changed considerably in recent years as molecular diagnostics have become incorporated with routine histopathology in the diagnostic process. This article will focus on the fundamental major histologic, immunohistochemical, and molecular features that neuropathologists use to make an integrated diagnosis of pediatric brain tumors. This concise review will focus on tumors that are integral to the central nervous system in pediatric patients including: embryonal tumors, low and high grade gliomas, glioneuronal tumors, ependymomas, and choroid plexus tumors.Copyright © Congress of Neurological Surgeons 2021. All rights reserved.

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