• Clin Exp Rheumatol · Jul 2005

    Case Reports

    Behçet's disease, myelodysplastic syndrome, trisomy 8, gastroenterological involvement--an association.

    • L Eder, M Rozenbaum, N Boulman, E Aayubkhanov, E Wolfovitz, D Zisman, and I Rosner.
    • Internal Medicine A, Carmel Medical Center, Haifa, Israel. ben@usha.org.il
    • Clin Exp Rheumatol. 2005 Jul 1; 23 (4 Suppl 38): S91-5.

    AbstractOnly a limited number of cases of Behçet's disease and hematological malignancies have been reported in the literature. We report the case of a 45 year old female patient with Behçet's disease who developed myelodysplastic syndrome, refractory anemia with excess blasts in transformation subtype, with complex chromosomal abnormalities, including excess of chromosome 8, following several years of treatment with chlorambucil for Behçet's disease. As has been described in most such cases, gastrointestinal involvement was most prominent. This case is described and the occurrence of myelodysplastic syndrome in Behçet's disease reviewed.

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