• Clinical cardiology · Sep 2015

    Multicenter Study Observational Study

    Rationale, Design, and Baseline Characteristics of the EPICOR Asia Study (Long-tErm follow-uP of antithrombotic management patterns In Acute CORonary Syndrome patients in Asia).

    • Yong Huo, Stephen W-L Lee, Jitendra P S Sawhney, Hyo-Soo Kim, Rungroj Krittayaphong, Vo T Nhan, Angeles Alonso-Garcia, Ya Ling Han, Junbo Ge, Chee Tang Chin, Tiong K Ong, Stephen Jan, Yohji Itoh, Ana Maria Vega, and Stuart Pocock.
    • Department of Cardiology, Peking University First Hospital, Beijing, China.
    • Clin Cardiol. 2015 Sep 1; 38 (9): 511-9.

    BackgroundIn-hospital and postdischarge mortality for acute coronary syndromes (ACS) vary across Asia and remain generally poorer than globally. The relationship between real-life antithrombotic management patterns (AMPs) and ACS-related outcomes in Asia is unclear.MethodsEPICOR Asia (Long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) (NCT01361386) is a prospective, multinational, observational study of patients discharged after hospitalization for an ACS, with 2-year follow-up. The aim is to describe short- and long-term (up to 2 years post-index event) AMPs in patients hospitalized for ACS and to record clinical outcomes, healthcare resource use, and self-reported health status. Pre- and in-hospital management, AMPs, and associated outcomes, with particular focus on ischemic and bleeding events, will be recorded during the 2-year follow up.ResultsBetween June 2011 and May 2012, 13 005 patients were enrolled. From these, 12 922 patients surviving an ACS (6616 with STEMI, 2570 with NSTEMI, and 3736 with UA) were eligible for inclusion from 219 hospitals across 8 countries and regions in Asia: China (n = 8214), Hong Kong (n = 177), India (n = 2468), Malaysia (n = 100), Singapore (n = 93), South Korea (n = 705), Thailand (n = 957), and Vietnam (n = 208).ConclusionsEPICOR Asia will provide information regarding clinical management and AMPs for ACS patients in Asia. Impact of AMPs on clinical outcomes, healthcare resource use, and self-reported health status both during hospitalization and up to 2 years after discharge will also be described.© 2015 Wiley Periodicals, Inc.

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