-
- A Maertens de Noordhout.
- Service universitaire de neurologie, Hôpital de la Citadelle, Bd du 12e de ligne, 4000 Liège, Belgique. al.maertens@chu.ulg.ac.be
- Rev Med Suisse. 2009 Aug 26; 5 (214): 1650-5.
AbstractThe cause of Parkinson's disease remains unknown and no cure or prevention exists so far. Levodopa remains by far the most potent symptomatic therapy, but induces side-effects such as motor fluctuations and abnormal movements, which can somewhat be counterbalanced by optimizing levodopa plasma levels or acting at receptors level with long half-life dopamine agonists. In severe cases, functional surgery with deep brain stimulation can be offered. Some non-dopaminergic symptoms like dementia, freezing, postural instability or dysautonomia do not respond to dopaminergic drugs and need special care.
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