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J. Thorac. Cardiovasc. Surg. · Feb 2013
Quality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms.
- Gabriele Di Luozzo, Aditya S Shirali, Robin Varghese, Hung-Mo Lin, Aaron J Weiss, Moritz S Bischoff, and Randall B Griepp.
- Department of Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, NY, USA. gabriele.diluozzo@mountsinai.org
- J. Thorac. Cardiovasc. Surg. 2013 Feb 1; 145 (2): 378-84.
ObjectiveWe assessed quality of life and survival in elderly patients after complex aortic operations to aid in surgical decision making.MethodsA retrospective review was performed of 93 patients who underwent descending thoracic aneurysm or thoracoabdominal aortic aneurysm (TAAA) repair from 2002 to 2008. A Cox model was used for survival analysis. The SF-36 Item Health Survey was administered to assess postoperative quality of life in 39 patients and was compared with age- and gender-matched normal scores.ResultsThe mean age at operation was 75 ± 4.1 years; 51% of patients were male. In-hospital mortality was 15%. One-year survival was 69%, and 5-year survival was 45%. Only acute respiratory distress syndrome was a predictor of in-hospital mortality (hazard ratio = 3.75; P < .01) and 1-year mortality (hazard ratio = 4.61; P < .001). After 1 year, patients enjoyed longevity equivalent to that of a normal age- and gender-matched population (standardized mortality ratio = 1.06; P = .81). Being male is a predictor of long-term survival (hazard ratio = 0.18; P < .05). For women, extremely low and high body mass indexes (quadratic term = 0.020; P < .05) with an inflection point of body mass index of 28 is a risk factor of long-term survival. Quality of life scores were similar to those of the general population except for lower vitality scores, (s-score = -0.67, 95% CI, -1.09 to -0.26).ConclusionsTAAA repair in this selected older surgical population yields acceptable survival beyond the first year. Among 1-year survivors, quality of life is similar to that of an age- and gender-matched population.Copyright © 2013 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
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