• J. Vasc. Surg. · Mar 2004

    Case Reports

    Methemoglobinemia: an unusual cause of postoperative cyanosis.

    • Carryn M Anderson, Kenneth J Woodside, Todd A Spencer, and Glenn C Hunter.
    • Division of Vascular Surgery, Department of Surgery, University of Texas Medical Branch, Boulevard, Galveston, TX 77555-0544, USA. gchunter@utmb.edu
    • J. Vasc. Surg. 2004 Mar 1; 39 (3): 686-90.

    AbstractMethemoglobinemia, although rare, must be considered in surgical patients presenting with acute respiratory distress and cyanosis. We report two cases of methemoglobinemia in patients undergoing aortic reconstruction. The first patient developed methemoglobinemia while on a nitroglycerin infusion, and the second after receiving benzocaine spray before intubation. Both patients were treated with methylene blue and ascorbic acid, with resolution of their hypoxia and cyanosis. The pathophysiology, etiology, diagnosis, and treatment of methemoglobinemia are reviewed.

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