• Crit Care Nurs Clin North Am · Sep 2017

    Review

    Balance Between the Proinflammatory and Anti-Inflammatory Immune Responses with Blood Transfusion in Sepsis.

    • Teresa C Rice, Amanda M Pugh, Charles C Caldwell, and Schneider Barbara St Pierre BSP The Tony and Renee Marlon Angel Network Professorship, School of Nursing, University of Nevada, Las Vegas, 4505 South Maryland Parkway, Bo.
    • Division of Research, Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
    • Crit Care Nurs Clin North Am. 2017 Sep 1; 29 (3): 331-340.

    AbstractBlood product transfusion may exacerbate the initial immunosuppressive response of sepsis. Nurses and other patient care providers must be diligent in recognizing and managing a worsening immune status, using flow cytometry to monitor patients' immune status. This type of monitoring may be instrumental in reducing morbidity and mortality in persons with sepsis. This article discusses the recent literature on the associated inflammatory responses that occur with blood transfusion and provides an analysis of alterations in key inflammatory pathways in response to transfusion in a sepsis population.Copyright © 2017 Elsevier Inc. All rights reserved.

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