• Babak Shadgan, Matthew Menon, Peter J O'Brien, and W Darlene Reid.
• Experimental Medicine, University of British Columbia, Vancouver, British Columbia, Canada. shadgan@interchange.ubc.ca
• J Orthop Trauma. 2008 Sep 1; 22 (8): 581-7.

ObjectivesTo review the efficacy of the current diagnostic methods of acute compartment syndrome (ACS) after leg fractures.Data SourcesA Medline (PubMed) search of the English literature extending from 1950 to May 2007 was performed using "compartment syndromes" as the main key word. Also a manual search of orthopaedic texts was performed.Study Selection And ExtractionThe results were limited to articles involving human subjects. Of 2605 primary titles, 489 abstracts limited to compartment syndromes in the leg and 577 articles related to the diagnosis of compartment syndromes were identified and their abstracts reviewed. Further articles were identified by reviewing the references. Sixty-six articles were found to be relevant to diagnostic techniques for compartment syndrome in the leg and formed the basis of this review.ConclusionsEarly diagnosis of an ACS is important. Despite its drawbacks, clinical assessment is still the diagnostic cornerstone of ACS. Intracompartmental pressure measurement can confirm the diagnosis in suspected patients and may have a role in the diagnosis of this condition in unconscious patients or those unable to cooperate. Whitesides suggests that the perfusion of the compartment depends on the difference between the diastolic blood pressure and the intracompartmental pressure. They recommend fasciotomy when this pressure difference, known as the Delta p, is less than 30 mm Hg. Access to a precise, reliable, and noninvasive method for early diagnosis of ACS would be a landmark achievement in orthopaedic and emergency medicine.

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