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Eur Arch Otorhinolaryngol · May 2020
Effect of prophylactic central neck dissection on the surgical outcomes in papillary thyroid cancer: experience in a single center.
- Dilek Yazıcı, Bülent Çolakoğlu, Burçin Sağlam, Havva Sezer, Yersu Kapran, Özlem Aydın, Mehmet Onur Demirkol, Faruk Alagöl, and Tarık Terzioğlu.
- Section of Endocrinology and Metabolism, Medical School, Koç University, Istanbul, Turkey. dyazici@ku.edu.tr.
- Eur Arch Otorhinolaryngol. 2020 May 1; 277 (5): 1491-1497.
PurposeMorbidity due to papillary thyroid carcinoma (PTC) is increased mostly due to lymph node (LN) metastases, which lead to reoperations and complications associated with these operations. The aim is to compare the outcomes of PTC having total thyroidectomy and prophylactic central lymph node dissection (TT + PCND) with patients having total thyroidectomy (TT) alone.MethodsThis study is a retrospective cohort analysis of 358 PTC patients that were operated by a single surgeon in a single center. Data about the patients were extracted from the medical records.ResultsOf the patient cohort, 258 patients had TT + PCND (42.5 ± 11.3 years) and 100 patients (41.2 ± 11.9 years) had only TT. Total number of LN extracted in the TT + PCND group was 8.1 ± 6.9. The mean number of metastatic LN were 2.2 ± 1.9. Percentage of patients that had RAI were less in the TT + PCND group compared to the TT group. Seven patients (2.7%) in the TT + PCND group and 19 (19.0%) in TT group had recurrent disease (p < 0.0001). Of the complications, only transient hypoparathyroidism was increased in TT + PCND group compared to TT group (26.7% vs 10%, p < 0.0001).ConclusionTT + PCND performed by an experienced surgeon seems to decrease the number of LN recurrences, and the need for reoperations.
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