• J. Nucl. Med. · Feb 2017

    Comparative Study

    Correlation Between SUVmax and CT Radiomic Analysis Using Lymph Node Density in PET/CT-Based Lymph Node Staging.

    • Frederik L Giesel, Florian Schneider, Clemens Kratochwil, Daniel Rath, Jan Moltz, Tim Holland-Letz, Hans-Ulrich Kauczor, Lawrence H Schwartz, Uwe Haberkorn, and Paul Flechsig.
    • Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.
    • J. Nucl. Med. 2017 Feb 1; 58 (2): 282-287.

    AbstractIn patients with lung cancer (LC), malignant melanoma (MM), gastroenteropancreatic neuroendocrine tumors (GEP NETs), and prostate cancer (PCA), lymph node (LN) staging is often performed by 18F-FDG PET/CT (LC and MM), 68Ga-DOTATOC PET/CT (GEP NET), and 68Ga-labeled prostate-specific membrane antigen PET/CT (PCA) but is sometimes not accurate because of indeterminate PET findings. To better evaluate malignant LN infiltration, additional surrogate parameters, especially in cases with indeterminate PET findings, would be helpful. The purpose of this study was to evaluate whether SUVmax in the PET examination might correlate with semiautomated density measurements of LNs in the CT component of the PET/CT examination.© 2017 by the Society of Nuclear Medicine and Molecular Imaging.

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