• Alan B Hollingsworth, Rebecca G Stough, Carol A O'Dell, and Charles E Brekke.
• Department of Surgery, Mercy Health Center, Oklahoma City, OK, USA. ahollingsworth@ok.mercy.net
• Am. J. Surg. 2008 Sep 1; 196 (3): 389-97.

BackgroundBreast magnetic resonance imaging (MRI) has been recommended increasingly in the preoperative setting for patients newly diagnosed with malignancy to evaluate tumor extent, multicentricity, and contralateral disease.MethodsResults of conventional imaging, breast MRI, and pathology were analyzed from 603 consecutive breast cancer patients who underwent MRI preoperatively. The focus of this retrospective study was imaging-histologic correlation.ResultsReoperation for positive margins after lumpectomy occurred in 8.8% of patients. Multicentricity was identified by MRI alone in 7.7% of patients, whereas 3.7% were found to have contralateral cancer by MRI. The sensitivity of MRI was 93% in detecting multicentric disease and 88% for contralateral disease, whereas sensitivity for conventional imaging was 46% and 19%, respectively. Unsuspected disease was identified by MRI equally for invasive ductal and ductal carcinoma in situ histology, whereas multicentricity was found more frequently with invasive lobular carcinoma.ConclusionsBreast MRI is recommended for preoperative evaluation of the newly diagnosed breast cancer patient.

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