• Internal medicine · Dec 2021

    Case Reports

    Acquired Hemophilia A Presenting with Infectious Aortic Aneurysms Due to an Underlying Helicobacter Cinaedi Infection: A Case Report.

    • Anna Matsuoka, Yuya Sasaki, Ai Kubodera, Kiyohito Hayashi, Ryo Shimizu, Akira Toriihara, Akira Nakamura, Keiichi Furukawa, and Hiroaki Tanaka.
    • Department of Internal Medicine, Asahi General Hospital, Japan.
    • Intern. Med. 2021 Dec 15; 60 (24): 3947-3952.

    AbstractAcquired hemophilia A (AHA) is a bleeding disorder caused by the acquired appearance of inhibitor for factor VIII. Approximately half of all patients with AHA have some type of underlying disease. We herein report the case of a 72-year-old Japanese man with AHA who presented with infectious aortic aneurysms due to an underlying Helicobacter cinaedi infection. To our knowledge, this is the first report of AHA triggered by a bacterial infection; however, there may be similar cases that remain undiagnosed because this pathogen is difficult to identify. Clinicians should consider the possibility of H. cinaedi as a causative pathogen in patients presenting with a fever of unknown origin.

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