• G Ital Cardiol (Rome) · Jun 2021

    [Thrombosis and COVID-19 vaccine: much ado about nothing?]

    • Vincenzo Toschi.
    • Servizio di Immunoematologia e Medicina Trasfusionale e Centro Emostasi e Trombosi, ASST Santi Paolo e Carlo, Milano.
    • G Ital Cardiol (Rome). 2021 Jun 1; 22 (6): 448-451.

    AbstractSeveral cases of thrombosis in unusual sites associated with thrombocytopenia have been described after vaccination with the recombinant adenoviral vector encoding the spike protein antigen of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ChAdOx1 nCov-19 (AstraZeneca) and Ad26.COV.2 (Johnson & Johnson/Janssen). This new clinical entity has many analogies with heparin-induced thrombocytopenia, and recent studies suggest that an immunologic mechanism may be implicated in the pathogenesis of this unusual thrombotic disorder. However, more data are needed to identify subjects at risk for this rare clotting disease.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…