-
Multicenter Study
Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.
- Caroline S Fox, Michael J Pencina, Peter W F Wilson, Nina P Paynter, Ramachandran S Vasan, and Ralph B D'Agostino.
- National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA. foxca@nhlbi.nih.gov
- Diabetes Care. 2008 Aug 1; 31 (8): 1582-4.
ObjectiveWe assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes.Research Design And MethodsParticipants were drawn from the original and offspring cohorts of the Framingham Heart Study. Lifetime (30-year) risk of CVD was assessed using a modified Kaplan-Meier approach adjusting for the competing risk of death, beginning from age 50 years.ResultsOver 30 years, the lifetime risk of CVD among women with diabetes was 54.8% among normal-weight women and 78.8% among obese women. Among normal-weight men with diabetes, the lifetime risk of CVD was 78.6%, whereas it was 86.9% among obese men.ConclusionsThe lifetime risk of CVD among individuals with diabetes is high, and this relationship is further accentuated with increasing adiposity.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..