• An Pediatr (Barc) · Feb 2014

    Case Reports

    [Posterior reversible encephalopathy syndrome: 5 chemotherapy related cases].

    • I San Martín García, R Urabayen Alberdi, V Díez Bayona, M Sagaseta de Ilúrdoz Uranga, J Esparza Estaun, J Molina Garicano, and S Berisa Prado.
    • Unidad de Oncohematología Infantil, Servicio de Pediatría, Complejo Hospitalario de Navarra B, Pamplona, España. Electronic address: i.sanmart@hotmail.com.
    • An Pediatr (Barc). 2014 Feb 1; 80 (2): 117-21.

    AbstractPosterior reversible encephalopathy syndrome, previously known as Reversible posterior leukoencephalopathy syndrome, is a clinical-radiological condition characterized by headache, altered mental functioning, seizures and visual alterations, with the magnetic resonance imaging showing cerebral edema, predominantly in the white matter with posterior distribution. Multiple clinical conditions can act as triggers. We present five oncology patients, four of them with acute lymphoblastic leukemia, receiving chemotherapy when they presented with this pathology. A prompt diagnosis, an appropriate therapy for hypertension, and a rapid control of the seizures are the keys to avoiding sequelae. Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

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