• Bulletin du cancer · Jan 2020

    Review

    [Research evolutions in immuno-oncology and their impact on the management of patients treated with immunotherapy].

    • Christophe Caux.
    • University of Lyon, Claude Bernard Lyon 1 university, centre Léon Bérard, Cancer research center of Lyon (CRCL), immunology department, Inserm 1052, CNRS 5286, 69008 Lyon, France; CRCL, Inserm U1052, team « Therapeutic Targeting of the Tumor Cells and Their Immune Stroma », 69008 Lyon, France. Electronic address: Christophe.caux@lyon.unicancer.fr.
    • Bull Cancer. 2020 Jan 1; 107 (1): 6-9.

    AbstractIn this brief note, we review the state of knowledge about biomarkers that influence the response to current immunotherapies and the impact of recent technological developments (single-cell analysis, multi-dimensional imaging) on the analysis of these biomarkers. Also, new developments and strategies around CAR-T cells and bispecific antibodies in immuno-oncology are presented.Copyright © 2020 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

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