• Diagn Interv Radiol · Jan 2013

    Case Reports

    Hybrid SPECT-CT with 99mTc-labeled red blood cell in a case of blue rubber bleb nevus syndrome: added value over planar scintigraphy.

    • Kalpa Jyoti Das, Punit Sharma, Niraj Naswa, Ramya Soundararajan, Rakesh Kumar, Chandrasekhar Bal, and Arun Malhotra.
    • Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
    • Diagn Interv Radiol. 2013 Jan 1; 19 (1): 41-3.

    AbstractBlue rubber bleb nevus syndrome (BRBNS) is a rare clinical entity characterized by multiple venous malformations (hemangiomas) of the skin and gastrointestinal tract. These hemangiomas usually cause episodes of occult gastrointestinal bleeding leading to iron deficiency anemia, and also carry a significant potential for serious hemorrhage. The 99mechnetium (99mTc)-labeled red blood cell scintigraphy has traditionally been utilized in the localization of occult bleeding sites in patients with suspected vascular malformations, angiodysplasia, and Meckel’s diverticulum. We report the incremental value of 99mTc-labeled red blood cell hybrid single-photon emission computed tomography-computed tomography (SPECT-CT) over planar scintigraphy alone in a 12-year-old female patient with BRBNS.

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