• A Shiotani, C Mukobayashi, H Oohata, T Yamanishi, T Hara, H Itoh, and S Nishioka.
• Second Department of Internal Medicine, Wakayama Medical College, Bancho.
• Intern. Med. 1997 Jul 1; 36 (7): 514-8.

AbstractWe treated a patient with an atypical presentation of Wegener's granulomatosis (WG) with dural involvement as the initial clinical manifestation. A 37-year-old man had a dural lesion without lower respiratory tract or renal manifestations in the initial clinical course. His only initial symptom was headache, and at disease onset computed tomography (CT) and magnetic resonance imaging (MRI) of the head revealed bilateral abnormal subdural masses. The diagnosis of WG was made based on the results of needle biopsy of the nasal polyps and the finding of positive circulating antineutrophil cytoplasmic antibodies (c-ANCA). He achieved remission on daily prednisone and cyclophosphamide with the later addition of sulfamethoxazole-trimethoprim.

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