• Nianfei Wang, Mingjun Zhang, Tong Sun, Huaidong Chen, Zhonglian Huang, Long Yan, Longsheng Wang, Fei Li, and Zhendong Chen.
• Oncology Department, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province 230601, China.
• Eur J Radiol. 2012 Jul 1; 81 (7): 1662-6.

ObjectiveTo compare diffusion weighted whole body imaging with background body signal suppression (DWIBS) with hybrid Positron Emission Computed Tomography (HPET/CT) on clinical value in oncology.Methods43 patients with oncological diseases were enrolled in our hospital from October, 2008 to April, 2010. All the cases underwent DWIBS and HPET/CT within 14 days. Combined with other imagings, lesions detected by both modalities were evaluated. Lesions were confirmed by pathology, cytology or clinical diagnosis (needed no less than 6 months and three times follow-up).ResultsThe overall detection rate of the DWIBS and HPET/CT were 90.3% (261/289), 86.6% (251/289), concordant ratio of the two modalities was 88.2% (255/289). There was no statistical difference between DWIBS and HPET/CT on detecting lesions (P>0.05). HPET/CT was significantly more sensitive in detecting lesions in lung (P<0.05), whereas DWIBS was more sensitive in identifying lesions in brain and bone (P<0.05). With regard to finding lesions in liver and lymph node, the two procedures had no significant difference (P>0.05).ConclusionDWIBS and HPET/CT have a certain degree of consistency in terms of identifying lesions. However, they have advantages and disadvantages in some organs or tissues, which should be taken into full consideration in clinical practice.Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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