• J Craniomaxillofac Surg · Jan 2015

    Randomized Controlled Trial Comparative Study

    Intra-articular platelet-rich plasma injection for the treatment of temporomandibular disorders and a comparison with arthrocentesis.

    • Mustafa Hancı, Mehtap Karamese, Zekeriya Tosun, Tahsin Murad Aktan, Selcuk Duman, and Nedim Savaci.
    • Istanbul Medipol University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Istanbul, Turkey.
    • J Craniomaxillofac Surg. 2015 Jan 1; 43 (1): 162-6.

    BackgroundTemporomandibular joint (TMJ) internal derangements are progressive painful conditions and cause joint dysfunction, joint sound, malocclusion, and locking of the mouth. Conservative and invasive techniques can be used for the treatment of TMJ internal derangements. The objective of the present study was to examine the benefit of an intra-articular platelet-rich plasma (PRP) injection and to compare this with arthrocentesis.MethodsTwenty patients (female: male; 15:5; age 26, 3 ± 9.3 years) for a total of 32 joints with reducible anterior disc dislocation, as confirmed by Magnetic Resonance Imaging (MRI), were divided into two groups. PRP was used for the study group, and arthrocentesis was used for the control group. Pain intensity, maximal interincisal opening, and TMJ sounds were assessed and compared for evaluation of treatment success.ResultsThere was a statistically significant reduction in pain intensity and joint sound and an increase in mouth opening in the study group when compared with the control group.ConclusionsThis study shows that intra-articular PRP injection for the treatment of reducible disc displacement of the TMJ is a more effective method than arthrocentesis.Copyright © 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

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