• F D'Amore, G Vinacci, E Agosti, L P Cariddi, A V Terrana, F A Vizzari, M Mauri, and A Giorgianni.
• From the Departments of Neuroradiology (F.D., A.V.T., F.A.V., A.G.).
• AJNR Am J Neuroradiol. 2020 Oct 1; 41 (10): 1800-1803.

AbstractSince December 2019, a novel Severe Acute Respiratory Syndrome coronavirus 2 from China has rapidly spread worldwide. Although respiratory involvement is the mainstay of coronavirus disease 2019 (COVID-19), systemic involvement has recently drawn more attention. In particular, a number of recent articles have shed light on the nervous system as one of the possible targets. At our institution, we observed 15 patients with acute brain vascular manifestations; most interesting, we had a higher prevalence of the posterior circulation acute impairment. In our series, 7 patients had acute posterior cerebral injury: 1, hemorrhagic posterior reversible encephalopathy syndrome; 5, posterior circulation ischemic stroke; and 1, parieto-occipital hemorrhagic stroke. On the basis of our evidence and previous basic science reports, we believe a common etiopathogenetic thread may connect ischemic/hemorrhagic events of the posterior circulation and posterior reversible encephalopathy syndrome in the setting of COVID-19.© 2020 by American Journal of Neuroradiology.

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