• Can Anaesth Soc J · Jan 1975

    Chloroprocaine-bupivacaine sequence for obstetric extradural analgesia.

    • E A Villa and G F Marx.
    • Can Anaesth Soc J. 1975 Jan 1; 22 (1): 76-8.

    AbstractTwo case reports, one a vaginal delivery, the other a Caesarean Section, have been presented to demonstrate the rationale of employing a chloroprocaine-bupivacaine sequence for extradural analgesia in obstetrics. Use of chloroprocaine for initiation and bupivacaine for maintenance of the block offers at least three advantages: (1) onset of pain relief is prompt while duration is prolonged; (2) more than one "test" dose of chloroprocaine may be employed with safety in rapid succession; (3) two drugs with different metabolic patterns are used, each in reduced amount.

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