• Xiaobing Fan, Hiroyuki Abe, Milica Medved, Sean Foxley, Sanaz Arkani, Marta A Zamora, Olufunmilayo I Olopade, Gillian M Newstead, and Gregory S Karczmar.
• Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA.
• J Magn Reson Imaging. 2006 Dec 1; 24 (6): 1311-5.

PurposeTo compare conventional fat-suppressed MR images of the breast to images derived from high spectral and spatial resolution MR data. Image quality and the level of fat suppression are compared qualitatively and quantitatively.Materials And MethodsWomen with suspicious breast lesions found on X-ray mammography were imaged on 1.5 Tesla GE SIGNA scanners. High spectral and spatial resolution (HiSS) data were acquired using echo-planar spectroscopic imaging. Images with intensity proportional to the water signal peak height in each voxel were synthesized. Conventional fat-suppressed images were acquired using a frequency selective inversion method. The experimental (HiSS) and conventional images were compared by experienced radiologists to evaluate the quality of fat suppression. In addition, fat suppression and image quality were evaluated quantitatively.ResultsFat suppression, tumor edge delineation, lesion conspicuity, and image texture were improved in the peak height images derived from HiSS data.ConclusionThe results demonstrate that the water peak height images obtained from HiSS data potentially could improve the quality of fat suppression, detection and diagnosis of breast cancer. HiSS allowed detection of lesions and evaluation of lesion morphology prior to contrast media injection. J. Magn. Reson. Imaging 2006. (c) 2006 Wiley-Liss, Inc.

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