• L Gargouri, I Maaloul, T Kamoun, B Maalej, F Safi, I Majdoub, M Hachicha, and A Mahfoudh.
• Department of pediatrics, pediatric emergency and intensive care, Hedi Chaker Hospital, route El Aïn, 3029 Sfax, Tunisia; Faculty of Medecine, Sfax, Tunisia. Electronic address: abdelhedigargourilamia@yahoo.fr.
• Arch Pediatr. 2015 Jun 1; 22 (6): 616-20.

ObjectivesPseudomonas aeruginosa sepsis usually carries a high mortality rate in immunocompromised children. Ecthyma gangrenosum is a known cutaneous manifestation due mainly to Pseudomonas infection with or without septicemia. We describe clinical, biological, and therapeutic data.Patients And MethodsOf those children admitted to the pediatric intensive care unit, three pediatric cases of community-acquired P. aeruginosa septicemia associated with ecthyma gangrenosum were retrospectively reviewed.ResultsThe three patients were aged 5 months, 9 months, and 1 year. Underlying hypogammaglobulinemia was detected in the oldest patient. Pseudomonas aeruginosa was isolated in all patients in blood and once in cultures of skin lesions and endotracheal aspirate. Two deaths occurred due to septic shock and multisystem organ failure despite numerous aggressive resuscitation attempts.ConclusionsP. aeruginosa sepsis should be treated as early as possible. Recognition of ecthyma gangrenosum allows early diagnosis and prescription of adequate antibiotic therapy without awaiting blood culture reports.Copyright © 2015 Elsevier Masson SAS. All rights reserved.

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