• Turkish J Pediatr · Jan 2019

    Case Reports

    An adolescent case of extensive Behçet`s disease successfully treated with Infliximab.

    • Emel Isıyel, Sevcan Bakkaloğlu, Deniz Oğuz, İdil Yenicesu, Öznur Boyunağa, Yeşim Özdemir, Çağrı Damar, Yaşar Kandur, Meltem Akçaboy, Ayşe Tana Aslan, Tuğba Şişmanlar, Enver Hasanoğlu, and Necla Buyan.
    • Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey.
    • Turkish J Pediatr. 2019 Jan 1; 61 (4): 585-588.

    AbstractIsıyel E, Bakkaloğlu S, Oğuz D, Yenicesu İ, Boyunağa Ö, Özdemir Y, Damar Ç, Kandur Y, Akçaboy M, Aslan AT, Şişmanlar T, Hasanoğlan E, Buyan N. An adolescent case of extensive Behçet`s disease successfully treated with Infliximab. Turk J Pediatr 2019; 61: 585-588. Cardiac involvement is an uncommon and life-threatening complication of Behçet`s Disease. We present a 14-year-old boy, admitted to our hospital for recurrent hemoptysis. In his radiologic evaluation, a right ventricular thrombus and pulmonary arterial aneurysm were identified. He was diagnosed with Behçet`s Disease, and then he received prednisone and cyclophosphamide. However, his cardiac thrombus enlargened. After his treatment was replaced with infliximab, the pulmonary aneurysms regressed, and the cardiac thrombus disappeared. In conclusion, infliximab should be considered as a reliable option for vascular Behçet`s Disease resistant to conventional treatment.

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