• Daniela Adamo, Antonio Celentano, Elvira Ruoppo, Claudia Cucciniello, Giuseppe Pecoraro, Massimo Aria, and Michele D Mignogna.
• Department of Neurosciences, Reproductive and Odontostomatological Sciences.
• Pain Med. 2015 Nov 1; 16 (11): 2171-9.

ObjectiveTo compare sociodemographic and clinical characteristics in patients with burning mouth syndrome (BMS) and their relationship with pain.DesignCross-sectional clinical study.SettingUniversity-Hospital.Subjects75 BMS patients were enrolled.MethodsThe study was conducted between September 2011 and March 2012 at the "Federico II" University of Naples. Demographic characteristics and clinical information including age, sex, educational level, marital status, job status, age at disease onset, oral symptoms, and triggers were collected via questionnaire interviews. To assess pain intensity the visual analogue scale (VAS) was administered. Descriptive statistics were collected, and Pearson Chi-square tests, Kruskal-Wallis nonparametric tests and the Spearman bivariate correlation were performed.ResultsThe mean age was 61.17 (±11.75, female/male ratio = 3:1). The mean age at disease onset was 56.75 (±12.01). A low educational level (8.57 ± 4.95) and 80% of unemployment were found. Job status and age at disease onset correlated with the VAS scale (P = 0.019 and P = 0.015, respectively). Tongue morphology changes, taste disturbances, and intraoral foreign body sensation have a significant dependence on gender (P = 0.049, 0.001, and 0.045, respectively); intraoral foreign body sensation has a significant dependence on marital status (P = 0.033); taste disturbances have a significant dependence on job status. (P = 0.049); xerostomia has a significant dependence on age (P = 0.039); and tongue color changes and a bitter taste have a significant dependence on educational level (P = 0.040 and 0.022, respectively). Marital status and educational level have a significant dependence on the triggers (P = 0.036 and 0.049, respectively).ConclusionsThe prevalence of BMS is higher in women, and in married, unemployed, and less highly educated patients. Burning is the most frequent symptom while stressful life events are the most frequent trigger reported.Wiley Periodicals, Inc.

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