• Neuroradiology · Apr 2014

    Dual-energy CT for detection of contrast enhancement or leakage within high-density haematomas in patients with intracranial haemorrhage.

    • Yoshiyuki Watanabe, Akio Tsukabe, Yuki Kunitomi, Mitsuo Nishizawa, Atsuko Arisawa, Hisashi Tanaka, Kazuhisa Yoshiya, Takeshi Shimazu, and Noriyuki Tomiyama.
    • Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan, watanabe@radiol.med.osaka-u.ac.jp.
    • Neuroradiology. 2014 Apr 1; 56 (4): 291-5.

    IntroductionOur study aimed to elucidate the diagnostic performance of dual-energy CT (DECT) in the detection of contrast enhancement in intracranial haematomas (ICrH) with early phase dual-energy computed tomography angiography (CTA) and compare the results with those obtained by delayed CT enhancement.MethodsThirty-six patients with ICrH were retrospectively included in this study. All patients had undergone single-energy non-contrast CT and contrast-enhanced dual-source DECT. DECT images were post-processed with commercial software, followed by obtaining iodine images and virtual non-contrast images and generating combined images that created the impression of 120-kVp images. Two neuroradiologists, blinded to the patients' data, reviewed two reading sessions: session A (non-contrast CT and combined CT) and session B (non-contrast CT, combined CT, and iodine images) for detection of contrast enhancement in the haematomas.ResultsContrast leakage or enhancement was detected in 23 (57.5 %) out of 40 haemorrhagic lesions in 36 patients on delayed CT. Three enhanced lesions were depicted only in the DECT iodine images. The sensitivity, specificity, positive predictive value, and negative predictive value of session A were 82.6, 94.1, 95.0, and 80.0 %, respectively, and those of session B were 95.7, 94.1, 95.7, and 94.1 %, respectively.ConclusionDECT emphasised the iodine enhancement and facilitated the detection of contrast enhancement or leakage.

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