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Case Reports
Non-African Burkitt lymphoma presenting with oral thrush and an orbital mass in a child.
- C Edelstein, J A Shields, C L Shields, P De Potter, R C Eagle, L Turtel, and N Hagstrom.
- Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.
- Am. J. Ophthalmol. 1997 Dec 1; 124 (6): 859-61.
PurposeTo report an unusual case of orbital involvement with non-African Burkitt lymphoma in a child.MethodsA 26-month-old boy developed oral thrush and painless right proptosis with eyelid swelling. Magnetic resonance imaging disclosed a diffuse mass involving the inferior, lateral, and superior right orbit and both maxillary sinuses. Incisional biopsy of the orbital mass was performed.ResultsHistopathology disclosed diffuse infiltration of the orbital tissues by a high-grade lymphoid neoplasm that showed positive immunoreactivity for B-cell markers. Immunoglobulin gene rearrangement studies disclosed a characteristic t(8;14) translocation consistent with a small, noncleaved malignant lymphoma of the Burkitt type.ConclusionNon-African Burkitt lymphoma may manifest with orbital involvement.
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