• Jaafar Basma, Christos Anagnostopoulos, Sylvain El-Khoury, Antoine Courban, Andrew J Gienapp, and Kenan Arnautovic.
• Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA. Electronic address: jbasma@uthsc.edu.
• World Neurosurg. 2021 Aug 1; 152: 71-79.

AbstractThe link between ancient Greek medicine and the Arabic translation period in the 9th century cannot be understood without studying the contributions of Syriac scholars. With their mastery of Greek and the related Semitic languages of Syriac and Arabic, they initiated a scientific translation process with methods that prevail to this day. In this paper, we reviewed Hunayn Ibn Isshaq's Ten Treatises on the Eye to elucidate the original contributions of the Syriac physicians to the field of neurologic surgery. We analyzed the oldest known diagram of orbital anatomy along with Hunayn's genuine ideas on the optic nerve anatomy and pathology, optic chiasm, afferent pupillary reflex, and papilledema and venous congestion. We also reviewed the neurosurgical elements found in the Syriac Book of Medicines including the thought process in localizing neurologic deficits based on clinical experience and anatomic dissections and the earliest recorded description of brachial plexus pathology.Copyright © 2021 Elsevier Inc. All rights reserved.

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