• Internal medicine · Dec 2021

    Case Reports

    Duchenne Muscular Dystrophy Successfully Treated with Aripiprazole in a Patient with Autism Spectrum Disorder Symptoms Including Irritability.

    • Seiya Noda, Ayuka Murakami, Seigo Kimura, Makoto Minamiyama, Masahisa Katsuno, and Satoshi Kuru.
    • Department of Neurology, Nagoya University Graduate School of Medicine, Japan.
    • Intern. Med. 2021 Dec 15; 60 (24): 3983-3986.

    AbstractDuchenne muscular dystrophy (DMD) is associated with neuropsychiatric disorders, and patients often present with autism spectrum disorder (ASD). We herein report a case of DMD accompanied by ASD that was successfully treated with aripiprazole, an atypical antipsychotic that has been used for treating irritability in child and early adolescent patients with ASD. The patient was diagnosed as having DMD at 3 years of age. Although he developed severe psychotic symptoms including irritability, insomnia, hallucinations, and delusions at 17 years of age, all the symptoms were successfully treated with aripiprazole without any detectable side effects.

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