• Michiko Sugita, Hana Harada, and Tatsuo Yamamoto.
• Department of Anesthesiology, Kumamoto University Hospital, 1-1-1 Honjo, Kumamoto, 860-8556, Japan. msugita@kumamoto-u.ac.jp
• J Anesth. 2012 Aug 1;26(4):595-7.

AbstractResistance to thyroid hormone (RTH) is a rare, predominantly inherited syndrome that involves impaired tissue responsiveness to thyroid hormones. We describe the perioperative management of a patient with RTH who underwent total thyroidectomy. Although surgery performed under general anesthesia was uneventful, after the surgery the patient developed difficult-to-treat hypocalcemia that lasted until postoperative day 4. Moreover, thyroid function even after discharge remained unstable despite replacement therapy. We suggest that the parathyroid and thyroid function of patients with RTH be followed very closely and that nociceptive stimulus of the surgery and postoperative pain be reduced as much as possible.

32 keywords...

hide…