• Neural Regen Res · Dec 2013

    Immediate versus delayed primary nerve repair in the rabbit sciatic nerve.

    • Ahmet Piskin, Berrin Zühal Altunkaynak, Atilla Çitlak, Hicabi Sezgin, Ozgür Yazιcι, and Süleyman Kaplan.
    • Department of Orthopedics and Traumatology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
    • Neural Regen Res. 2013 Dec 25; 8 (36): 3410-5.

    AbstractIt is well known that peripheral nerve injury should be treated immediately in the clinic, but in some instances, repair can be delayed. This study investigated the effects of immediate versus delayed (3 days after injury) neurorrhaphy on repair of transected sciatic nerve in New Zealand rabbits using stereological, histomorphological and biomechanical methods. At 8 weeks after immediate and delayed neurorrhaphy, axon number and area in the sciatic nerve, myelin sheath and epineurium thickness, Schwann cell morphology, and the mechanical property of nerve fibers did not differ obviously. These results indicate that delayed neurorrhaphy do not produce any deleterious effect on sciatic nerve repair.

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