• Bulletin du cancer · Dec 2012

    Review

    [Esthesioneuroblastoma].

    • Fatma Elloumi, Noureddine Boujelbene, Lilia Ghorbal, Nadia Boujelbene, Khaouthar Khanfir, René-Olivier Mirimanoff, and Jamel Daoud.
    • Centre hospitalier universitaire Habib Bourguiba, service de radiothérapie carcinologique, route el Aïn Km 0.5, 3029 Sfax, Tunisie.
    • Bull Cancer. 2012 Dec 1; 99 (12): 1197-207.

    AbstractEsthesioneuroblastoma is an uncommon malignancy originating from olfactive epithelium. Men are more frequently affected than women. Nasal symptoms are the most common revealing signs. Immunohistochemistry helps diagnosis. There is no randomized trial evaluating treatment due to the low incidence of this tumor. Radiotherapy and surgery are the standard of care. Radiotherapy is benefic even in early stage disease. Chemotherapy is indicated in case of locally advanced or metastatic disease.

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