• J. Obstet. Gynaecol. Res. · Nov 2015

    Case Reports

    Antepartum reversible cerebral vasoconstriction syndrome with pre-eclampsia and reversible posterior leukoencephalopathy.

    • Kei Tanaka, Miho Matsushima, Yukiko Matsuzawa, Yuichi Wachi, Tomoko Izawa, Keiji Sakai, Yoichi Kobayashi, and Mitsutoshi Iwashita.
    • Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Tokyo, Japan.
    • J. Obstet. Gynaecol. Res. 2015 Nov 1; 41 (11): 1843-7.

    AbstractReversible cerebral vasoconstriction syndrome (RCVS) is characterized by severe headache and diffuse segmental constriction of the cerebral arteries that resolves spontaneously within a few months. Pregnancy is one of the precipitating factors of RCVS and most of the reported cases occurred in the post-partum period. We report a case of RCVS that occurred in a pregnant women with pre-eclampsia during her antepartum period. A 34-year-old woman in full-term pregnancy presented with a severe and acute headache. Magnetic resonance angiography (MRA) showed multiple segmental constrictions of the cerebral arteries. Magnetic resonance imaging revealed a high-intensity lesion in the left occipital lobe, consistent with reversible posterior leukoencephalopathy syndrome, on fluid attenuated inversion recovery sequences. The case was also complicated by severe pre-eclampsia and the patient underwent emergency cesarean section. Although her symptoms resolved rapidly, MRA revealed new lesions of arterial constriction 4 days after onset. The vasoconstriction completely resolved on MRA after 10 days and the patient was discharged without neurological sequelae. © 2015 Japan Society of Obstetrics and Gynecology.

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