• Clinical rheumatology · Aug 2007

    Case Reports

    Low-dose intra-venous cyclophosphamide therapy in a patient with neurological complications of Behçet's disease.

    • N Melillo, S Sangle, M R Stanford, T C Andrews, and D P D'Cruz.
    • Lupus Research Unit, The Rayne Institute, Lambeth Wing, St. Thomas' Hospital, London, SE1 7EH, UK.
    • Clin. Rheumatol. 2007 Aug 1; 26 (8): 1365-7.

    AbstractBehçet's disease (BD) is a chronic relapsing-remitting inflammatory disorder of unknown origin, affecting multiple organs. Neurological involvement is one of the most devastating manifestations of BD and may be fatal. We report a 36-year-old woman with neuro-Behçet who was treated with low-dose pulse cyclophosphamide (St. Thomas' protocol) and methylprednisolone, with almost complete clinical remission.

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