• Abdominal imaging · Aug 2015

    Case Reports

    (68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer.

    • Matthias Eiber, Stephan G Nekolla, Tobias Maurer, Gregor Weirich, Hans-Jürgen Wester, and Markus Schwaiger.
    • Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany, matthias.eiber@tum.de.
    • Abdom Imaging. 2015 Aug 1; 40 (6): 1769-71.

    AbstractCurrent imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.

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