• Korean J Radiol · Mar 2013

    Case Reports

    F-18 fluorodeoxyglucose PET/CT and post hoc PET/MRI in a case of primary meningeal melanomatosis.

    • Hong Je Lee, Byeong-Cheol Ahn, Seong Wook Hwang, Suk Kyong Cho, Hae Won Kim, Sang-Woo Lee, Jeong-Hyun Hwang, and Jaetae Lee.
    • Department of Nuclear Medicine, Dongnam Institute of Radiological & Medical Sciences, Busan 619-953, Korea.
    • Korean J Radiol. 2013 Mar 1; 14 (2): 343-9.

    AbstractPrimary meningeal melanomatosis is a rare, aggressive variant of primary malignant melanoma of the central nervous system, which arises from melanocytes within the leptomeninges and carries a poor prognosis. We report a case of primary meningeal melanomatosis in a 17-year-old man, which was diagnosed with (18)F-fluorodeoxyglucose (F-18 FDG) PET/CT, and post hoc F-18 FDG PET/MRI fusion images. Whole-body F-18 FDG PET/CT was helpful in ruling out the extracranial origin of melanoma lesions, and in assessing the therapeutic response. Post hoc PET/MRI fusion images facilitated the correlation between PET and MRI images and demonstrated the hypermetabolic lesions more accurately than the unenhanced PET/CT images. Whole body F-18 FDG PET/CT and post hoc PET/MRI images might help clinicians determine the best therapeutic strategy for patients with primary meningeal melanomatosis.

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