• Clinical nuclear medicine · Oct 2015

    Case Reports

    Talc Pleurodesis With Intense 18F-FDG Activity But No 68Ga-DOTA-TATE Activity on PET/CT.

    • Georgios Z Papadakis, Corina Millo, Ulas Bagci, Nicholas J Patronas, and Constantine A Stratakis.
    • From the *Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center; †Division of Nuclear Medicine, RAD&IS, Clinical Center, National Institutes of Health; ‡Center for Research in Computer Vision, University of Central Florida, Orlando, FL; and §Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, MD.
    • Clin Nucl Med. 2015 Oct 1; 40 (10): 819-20.

    AbstractTalc pleurodesis (TP) is a technique, widely employed in the management of patients with persistent pleural effusions or pneumothoraces not amenable to other treatment options. It is well documented that talc deposits produce areas of highly increased F-FDG uptake, because of talc-induced inflammation. We present a case of a patient with history of TP who was evaluated with both F-FDG and Ga-DOTA-TATE. The hypermetabolic area seen on F-FDG-PET-CT in the region of talc placement showed no uptake by Ga-DOTA-TATE, suggesting the potential role of Ga-DOTA-TATE-PET-CT in elucidating F-FDG-postitive lesions in patients with history of both neuroendocrine malignancy and TP.

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