• Expert review of vaccines · Apr 2012

    Review

    A prophylactic quadrivalent vaccine for the prevention of infection and disease related to HPV-6, -11, -16 and -18.

    • Stephen E Goldstone and Scott Vuocolo.
    • Mount Sinai School of Medicine, 420 West 23rd Sreet, New York, NY, USA. segmd@prodigy.net
    • Expert Rev Vaccines. 2012 Apr 1; 11 (4): 395-406.

    AbstractHuman papillomavirus infection causes cervical cancer, a significant portion of anal, genital and oropharyngeal cancers, genital warts and recurrent respiratory papillomatosis. In June 2006, a quadrivalent human papillomavirus-6/11/16/18 vaccine (GARDASIL/SILGARD®; Merck, NJ, USA) was licensed in the USA; subsequent approval has been granted in the EU (September 2006). It has since been approved in 121 countries with over 74 million doses distributed globally as of March 2011.

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