• Nucl Med Rev Cent East Eur · Jan 2010

    Role of F-18-FDG-PET/CT in restaging of patients affected by gastrointestinal stromal tumours (GIST).

    • Francesco Bertagna, Giovanni Bosio, Emanuela Orlando, Giorgio Biasiotto, and Raffaele Giubbini.
    • Nuclear Medicine, Spedali Civili di Brescia, Brescia, Italy. francesco.bertagna@spedalicivili.brescia.it
    • Nucl Med Rev Cent East Eur. 2010 Jan 1; 13 (2): 76-80.

    BackgroundGastrointestinal stromal tumours (GISTs) are a subset of mesenchymal tumours that represent the most common mesenchymal neoplasms of the gastrointestinal (GI) tract and account for less than 1% of all gastrointestinal tumours.Material And MethodsWe retrospectively evaluated 19 patients (6 females and 13 males; median age: 61 years ± 15 standard deviation) affected by GIST histologically documented after surgical intervention or biopsy.ResultsF18-FDG-PET/CT had identified pathologic uptakes and was considered positive for neoplastic tissue in 10 patients (53%) and negative in 9 (47%), in concordance with radiological findings.ConclusionsF18-FDG-PET/CT is a feasible, reliable, and accurate method to restage patients affected by previously histologically confirmed GIST, also in the absence of a staging study.

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