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- M Cabrerizo, T De Miguel, A Armada, R Martínez-Risco, A Pousa, and G Trallero.
- Virology Department, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain. mcabrerizo@isciii.es
- Epidemiol. Infect. 2010 Dec 1; 138 (12): 1775-8.
AbstractFew reports exist regarding the association between onychomadesis and an enterovirus infection presenting clinically as hand, foot, and mouth disease (HFMD). In February 2009, an outbreak of HFMD occurred in a Spanish nursery school, followed by onychomadesis 36-69 days later. Twelve of 17 children with HFMD developed nail shedding; enterovirus was detected in stool samples from eight (47%) of the 17. However, in only three of the children could an enterovirus serotype coxsackievirus B1 be identified. The epidemiological results of this study confirm onychomadesis as a complication in HFMD. In future outbreaks, molecular characterization of enterovirus from appropriate clinical samples should be studied.
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